Nunsense follows the crazy antics of five nuns from the Little Sisters of Hoboken convent. When their cook accidentally serves up some tainted soup, 52 of the sisters are poisoned and die, leaving only five living nuns who were not at home the day of the toxic meal. When the sisters find themselves strapped for cash, the nuns decide to put on a benefit performance in order to raise the rest of the money before the health department discovers their “chilling” secret.